The panel will explore the transformative potential of psychedelic medicine in addressing the psychospiritual needs of cancer patients. By alleviating existential distress, end of life anxiety, and depression, psychedelics offer a unique pathway to emotional healing and a deeper sense of meaning. The discussion will cover current research, therapeutic applications, and real-world experiences, highlighting how these medicines, when used in the appropriate settings, and with skilled support, can help patients navigate their journey with greater peace, resilience, and connection.