Circadian & Mitochondrial Medicine in Oncology: Integrating Light, Timing, and Metabolic Care for Breast and Prostate Cancer
Circadian disruption and impaired bioenergetics are increasingly recognised contributors to cancer risk, treatment tolerance, and survivorship outcomes. This session translates sleep and circadian science into integrative oncology practice for breast and prostate cancer, where night-time light exposure, irregular sleep–wake schedules, and metabolic dysregulation commonly coexist with standard therapy.
We present a pragmatic, clinician-friendly framework that complements (not replaces) conventional care: (1) Light hygiene prescriptions (morning daylight, evening blue/bright-light restriction, sleep regularity); (2) Chrono-behavioural care (timing of meals, exercise, and medications to reinforce central and peripheral clocks); (3) Metabolic optimisation (clinically supervised time-restricted eating when appropriate, low-glycaemic dietary patterns, resistance/aerobic training, vitamin D repletion); and (4) Targeted photobiomodulation for symptom relief (e.g., mucositis, pain, or post-surgical recovery) within accepted safety parameters.
Two anonymised vignettes illustrate implementation: ER+ breast cancer with metabolic syndrome, and high-risk prostate cancer with androgen-deprivation-induced dysglycaemia. We will track outcomes relevant to oncology clinics—sleep efficiency, fatigue scores, fasting glucose/insulin (HOMA-IR), waist circumference, HRV, vitamin D status, patient-reported quality of life—alongside oncologic milestones.
Attendees leave with ready-to-use protocols (light exposure scripts, circadian-aligned meal and activity schedules, monitoring checklists), integration tips with chemo-/radio-/endocrine therapies, and cautions in vulnerable populations (e.g., cachexia). Framed within Integrative Oncology, Sleep & Circadian Rhythms, and Metabolic Health, this session offers a practical pathway to personalise care, support treatment tolerance, and improve patient well-being.

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