Biochemical Pathways in Chronic Lyme Disease: Mechanisms Underlying Persistent Symptoms

19 Jun 2026
Level 4 - Moore Room
Lyme Disease , Nutraceuticals

Lyme disease, caused by Borrelia burgdorferi and transmitted by ticks, can lead to persistent symptoms in some patients despite antibiotic treatment.  This lecture examines mechanisms behind chronic Lyme disease, including persister cells, biofilms, intracellular infection, immune dysregulation, and autoimmunity.  It highlights mitochondrial dysfunction, oxidative stress, and altered energy metabolism as key contributors to fatigue and cognitive issues, emphasizing the interplay of these processes in sustaining chronic symptoms.

Speakers
Pol De Saedeleer PhD
Pol De Saedeleer PhD, RPharmD, Scientific & Medical Director – Nutrined/Researched Nutritionals, Netherlands